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| Recipient | Buck Institute |
| City | Novato, CA |
| Description | To research the role of the aging process in the etiology of human disease.
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| Recipient | Northwestern University |
| City | Evanston, IL |
| Description | To examine whether zinc plays a central role in oocyte maturation and in mediating early signals in embryogenesis.
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| Recipient | Stanford University |
| City | Stanford, CA |
| Description | To support research using bioengineering technologies to study electrically excitable tissue in rodent models of neuropsychiatric, motor, and cardiac disease.
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|
| Recipient | City of Hope |
| City | Los Angeles, CA |
| Description | To continue work to understand the molecular mechanisms
underlying cancer and develop therapies that destroy lymphoma
cells without harming normal cells.
|
| Recipient | Arizona State University |
| City | Tempe, AZ |
| Description | To study frameshift peptides common in tumors as targets for development of a cancer vaccine.
|
| Recipient | Carnegie Mellon University |
| City | Pittsburgh, PA |
| Description | To research how the brain composes neural representations
of word and sentence meanings from their component parts.
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| Recipient | Stanford University |
| City | Stanford, CA |
| Description | To develop equipment to study the structure and dynamics of neural circuits.
|
| Recipient | Translational Genomics Research Institute |
| City | Phoenix, AZ |
| Description | To develop network models of biological function using signal processing and control theory.
|
| Recipient | University of California, Los Angeles |
| City | Los Angeles, CA |
| Description | To develop stem cell technology to engineer human immune cells for targeted cancer treatments.
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| Recipient | University of California, San Francisco |
| City | San Francisco, CA |
| Description | To characterize and understand the function of the non-protein coding RNA genes by developing new mouse models for human disease.
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| Recipient | University of Massachusetts Medical School |
| City | Worcester, MA |
| Description | To study how asymmetric cell division affects aging and longevity in somatic and stem cells.
|
| Recipient | University of Oregon |
| City | Eugene, OR |
| Description | To study biological interactions of engineered nanoparticles and establish fundamental design
rules for biomedical applications.
|
| Recipient | University of Texas - M. D. Anderson Cancer Center |
| City | Houston, TX |
| Description | To understand molecular mechanisms behind the generation
of immunosuppressive T-cells in the thymus and tumor microenvironment and to develop cancer immunotherapies.
|
|
| Recipient | City of Hope |
| City | Los Angeles, CA |
| Description | To understand the molecular mechanisms underlying cancer and develop new therapies that destroy lymphoma cells without harming normal cells.
|
| Recipient | Cold Spring Harbor Laboratory |
| City | Cold Spring Harbor, NY |
| Description | To map the architecture of the human and rodent brain and gain an insight into neural dynamics underlying motivated behavior.
|
| Recipient | Indiana University-Purdue University Indianapolis |
| City | Indianapolis, IN |
| Description | To understand the mechanisms of regeneration and restoration in amphibians and apply these mechanisms in potential therapies for spinal cord injury patients.
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| Recipient | Mount Sinai School of Medicine |
| City | New York, NY |
| Description | To study the pandemic risk of avian influenza viruses using an animal model of human transmission.
|
| Recipient | University of California, Berkeley |
| City | Berkeley, CA |
| Description | To establish a laboratory to research structures
and functions of the fundamental molecular machines that mediate information flow in cells and viruses.
|
| Recipient | University of Louisville |
| City | Louisville, KY |
| Description | To study the cellular and molecular mechanisms of facilitating-cell regulatory function on hematopoetic stem cells.
|
| Recipient | University of Michigan |
| City | Ann Arbor, MI |
| Description | To develop an integrated system of distributed microscale actuators, intracellular sensors and feedback controls capable of chemically interfacing with a developing embryo.
|
| Recipient | University of Pennsylvania |
| City | Philadelphia, PA |
| Description | To develop novel methods for understanding the cell types involved in neurodegenerative diseases like Parkinson's, and develop therapeutic interventions.
|
| Recipient | Washington State University |
| City | Pullman, WA |
| Description | To gain insight into the mechanisms underlying the phenomenon of sleep.
|
| Recipient | Yale University |
| City | New Haven, CT |
| Description | To map basic cellular networks in the brain and the immune system.
|
|
| Recipient | Dana-Farber Cancer Institute |
| City | Boston, MA |
| Description | To support the Human Interactome Project, which will provide insight into the networks of physical interactions among cellular proteins.
|
| Recipient | Oregon Health & Science University |
| City | Portland, OR |
| Description | To equip the Advanced Imaging Research Center
with a 11.75T animal MR imaging and spectroscopy system and develop high-resolution, high-sensitivity brain imaging
methodologies.
|
| Recipient | Oregon State University |
| City | Corvallis, OR |
| Description | To build an electron capture dissociation chamber to improve fragmentation of peptides and therefore data obtained from mass spectrometry.
|
| Recipient | Tufts University |
| City | Medford, MA |
| Description | To purchase instrumentation required for the study of complex interrelationships between the human immune
system and its disease-causing pathogens.
|
| Recipient | University of California, San Diego |
| City | La Jolla, CA |
| Description | For a tri-institutional collaboration to analyze
human stem cell differentiation pathways using extremely rapid robotic screening techniques.
|
| Recipient | University of California, Santa Barbara |
| City | Santa Barbara, CA |
| Description | To define the role of specific microRNAs in the
establishment and maintenance of neuronal identity.
|
| Recipient | University of New Mexico |
| City | Albuquerque, NM |
| Description | To study a newly identified class of steroid receptors
that are highly expressed in tumors, which will advance the development of new and more effective cancer treatments.
|
|
| Recipient | George Washington University |
| City | Washington, DC |
| Description | To combine a MALDI mass spectrometer with a scanning near-field optical microscope to obtain images of protein distribution in living
cells and tissues.
|
| Recipient | Jackson Laboratory |
| City | Bar Harbor, ME |
| Description | For research into gene function and expression at the cellular and subcellular levels using a new generation of confocal microscopy techniques.
|
| Recipient | Memorial Sloan-Kettering Cancer Center |
| City | New York, NY |
| Description | To explore the molecular and cellular mechanisms of cancer metastasis using imaging methods and molecular biology techniques.
|
| Recipient | Tulane University |
| City | New Orleans, LA |
| Description | To develop adult stem cells for research use, and specifically to study the molecular mechanisms used by stem cells to repair tissue damage.
|
| Recipient | University of Wisconsin, Madison |
| City | Madison, WI |
| Description | To study the biological mechanisms that cause undifferentiated embryonic stem cells to develop into cells with highly specific functions.
|
| Recipient | Washington University in St. Louis |
| City | St. Louis, MO |
| Description | To explore how the microbial community that inhabits the gut influences nutrition, immunity, cancer risks and other aspects of human health.
|
Medical Research Special Grant
|
| Recipient | Doheny Eye Institute |
| City | Los Angeles, CA |
| Description | To support the intraocular retinal prosthesis program.
|
|
| Recipient | Colorado State University |
| City | Fort Collins, CO |
| Description | To support research that will explore the role of chromatin structure in controlling gene expression.
|
| Recipient | Morehouse School of Medicine |
| City | Atlanta, GA |
| Description | To study the genes and proteins involved in neuronal regeneration and neurodegenerative disorders.
|
| Recipient | Neurosciences Institute |
| City | San Diego, CA |
| Description | To study the neural bases of perception, cognition, and behavior using a synthetic neural modeling system.
|
| Recipient | University of California, Los Angeles |
| City | Los Angeles, CA |
| Description | For a collaborative project to understand, diagnose and treat epithelial cancers using nanotechnology methods.
|
| Recipient | University of Colorado at Boulder |
| City | Boulder, CO |
| Description | To develop a facility to study single molecules of RNA, and for bioinformatics research to predict RNA structure and function.
|
| Recipient | University of Illinois at Urbana-Champaign |
| City | Champaign, IL |
| Description | To study molecules critical to nervous system development and to understand mechanisms for repairing damaged neuronal circuits.
|
| Recipient | University of Texas Medical Branch at Galveston |
| City | Galveston, TX |
| Description | To equip a virus imaging center in a biosafety level-3 laboratory for studying infectious diseases like West Nile and SARS.
|
| Recipient | Western Michigan University |
| City | Kalamazoo, MI |
| Description | To measure line tension, a force essential to the transport of materials into and out of cell membranes.
|
|
| Recipient | Fred Hutchinson Cancer Research Center |
| City | Seattle, WA |
| Description | To support the development of proteomic technology for an early identification of human susceptibility to cancers and other diseases.
|
| Recipient | Mayo Foundation |
| City | Rochester, MN |
| Description | To construct a highly sensitive mass spectrometer for protein analysis to aid early identification of disease or determine changes in proteins that contribute to disease.
|
| Recipient | University of California, Riverside |
| City | Riverside, CA |
| Description | To purchase proteomics instruments for the Genomics Institute to study functional genetics in key plants, insects, and pathogens that are important for protecting the world's food supply.
|
| Recipient | University of Michigan |
| City | Ann Arbor, MI |
| Description | To use nanoprobes for detection of rare ionic events in cells and model how these essential minerals are involved in health and disease.
|
| Recipient | University of Minnesota, Twin Cities |
| City | Minneapolis, MN |
| Description | To purchase a 9.4 Tesla/65cm MRI for the Center for Magnetic Resonance Research to develop ultra-high field methodologies for non-invasive longitudinal studies of the brains of humans and primates.
|
|
| Recipient | Baylor College of Medicine |
| City | Houston, TX |
| Description | To establish the Gulf Coast Consortium in Magnetic Resonance, combining the research strengths in computational and structural biology of six Houston-area universities and expanding existing training programs at the Keck Center for Computational Biology.
|
| Recipient | Duke University |
| City | Durham, NC |
| Description | To establish the W. M. Keck Center for Neuro-oncology Genomics that will apply new genomic, proteomic and bioinformatic technologies to characterize brain tumors and develop therapies targeted to specific tumors.
|
| Recipient | Johns Hopkins University |
| City | Baltimore, MD |
| Description | To establish the Center for the Rational Design of Biologically Active Molecules in the School of Medicine, which will facilitate synthetic organic chemistry approaches to biomedical problems.
|
| Recipient | Medical University of South Carolina |
| City | Charleston, SC |
| Description | To continue support for the Sea Islands Families Project, specifically to support the community-based efforts involved in the development of this unique genetic resource.
|
| Recipient | New York Structural Biology Center |
| City | New York, NY |
| Description | To purchase a 900 MHz NMR system for high-resolution studies of macromolecular structures for a consortium of ten institutions in the New York area.
|
| Recipient | University of California, San Francisco |
| City | San Francisco, CA |
| Description | To support the establishment of laboratory for the study of cellular function and to develop new imaging technologies for atomic- to cellular-level resolution.
|
| Recipient | University of Colorado Health Sciences Center |
| City | Denver, CO |
| Description | To purchase an 800 MHz NMR to be shared by UCHSC, UC Boulder and the University of Utah and establish the Keck Advanced High-Field NMR Center of the Rocky Mountain Region.
|
| Recipient | University of Iowa |
| City | Iowa City, IA |
| Description | To establish a multidisciplinary project in Microbial Communities and Cell Signaling conducted in collaboration with the Kewalo Marine Laboratory at the University of Hawaii.
|
| Recipient | University of Washington |
| City | Seattle, WA |
| Description | To support the Center for Functional, Structural and Chemical Genomics of Microbial Pathogens, which will apply new technologies to the worldwide problem of microbial pathogenicity.
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